GGT in Serum

Serum Gamma-glutamyl transferase usually originates from hepatocytes and cholangiocytes (plus pancreas).
Also known as:
Gamma-glutamyl transferase
S-GGT
.

GGT ranges for

Interpret your result
"Normal" lab range for GGT is between 11 and 62 IU/L for males:
11
62
According to OptimalDX, GGT should be between 10 and 17 IU/L:
10
17
Optimal range
Optimal range for GGT appears to be between 8 and 17 IU/L for males:
0
8
17
60
100
This isn't medical advice. Consult your healthcare provider.
Your interpretation
For high

Possible reasons for high GGT:

  • Major serum GGT contributors: Liver (both hepatocytes and cholestasis), gallbladder, pancreas and kidneys. Also increased in insulin resistance, toxin exposure, oxidative stress and increased antioxidants (glutathione) need etc.

    Drugs that can increase GGT: Alcohol, anti-seizure medications and more.

    ,

Possible consequences from high GGT:

  • Above 16.5 IU/L was associated with metabolic syndrome
  • Above 20.5 IU/L was associated with impaired glucose tolerance
  • Above 18 IU/L was associated with insulin resistance, prehypertension, and cancer,,

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Zsolt Szabo
Zsolt Szabo
Software Engineer, Biohacker, and Consultant for Longevity Clinics.

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I am particularly interested in research on biomarkers associated with all-cause mortality and on defining optimal reference ranges.