ApoB in Serum

ApoB is the best biomarker for assessing ASCVD risk, as it encompasses all atherogenic lipoprotein particles, including LDL, IDL, VLDL, and Lp(a).
Also known as:
Apolipoprotein B
S-ApoB
.

ApoB ranges

Interpret your result
"Normal" lab range for ApoB is between 60 and 130 mg/dL:
60
130
According to 2026 ACC/AHA/Multisociety Guideline, ApoB should be below 90 mg/dL:
90
According to Peter Attia, ApoB should be below 65 mg/dL:
65
According to OptimalDX, ApoB should be between 52 and 80 mg/dL:
52
80
Optimal range
Optimal range for ApoB appears to be below 30 mg/dL:
0
"Zero risk"
30
Low risk
70
Moderate risk
100
High risk
180
Why this optimal range?
Range is based on functional health organizations including but not limited to those listed above.
Your interpretation
For high

Common reasons for high ApoB:

  • Elevated ApoB is the primary driver of atherosclerotic cardiovascular disease (ASCVD), as each atherogenic lipoprotein particle carries exactly one ApoB molecule.

    Common causes: diets high in saturated fat and refined carbohydrates, insulin resistance, metabolic syndrome, type 2 diabetes, familial hypercholesterolemia, hypothyroidism, nephrotic syndrome, and obesity.

    Medications: androgens, progestins, diuretics, beta blockers.

    ,

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