AST in Serum

Transaminase released from hepatocytes and cardiac/skeletal muscle (with minor contributions from kidney, pancreas, brain, RBCs and gallbladder).
Also known as:
Aspartate Aminotransferase
S-AST
.

AST ranges for

Interpret your result
"Normal" lab range for AST is between 10 and 50 IU/L for males:
10
50
According to Peter Attia, AST should be below 25 IU/L for males:
25
According to OptimalDX, AST should be between 10 and 26 IU/L:
10
26
Optimal range
Optimal range for AST appears to be between 10 and 25 IU/L:
0
10
25
35
80
Why this optimal range?
Preliminary range is based on functional health organizations including but not limited to those listed above.
Your interpretation
For low
For high

Common reasons for high AST:

  • Elevated AST levels are seen in muscle injury (e.g., strenuous exercise, seizures, myopathies, myocardial infarction or heart failure), tissue damage (severe burns, surgery), liver injury (fatty liver, viral or other infections, malignancy), anorexia or rapid weight change (e.g., >5 kg/week), pancreatitis, gallbladder attack and hemolysis (e.g., hemolytic anemia, splenomegaly).

    Several drugs can increase AST including: chronic alcohol, NSAIDs, acetaminophen, oral contraceptives, statins, certain antibiotics, corticosteroids, toxins like lead, mercury, and pesticides.

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