ALP in Serum

Alkaline phosphatase is primarily released from the bile ducts and bone. Minor sources include the intestinal mucosa, kidneys, and placental tissue (during pregnancy).
Also known as:
Alkaline Phosphatase
S-ALP
ALKP
ALPase
.

ALP ranges for

Interpret your result
"Normal" lab range for ALP is between 40 and 130 IU/L for males:
40
130
According to OptimalDX, ALP should be between 45 and 100 IU/L:
45
100
Optimal range
Optimal range for ALP appears to be between 50 and 100 IU/L for males:
20
40
50
100
130
180
Why this optimal range?
Preliminary range is based on functional health organizations including but not limited to those listed above.
Your interpretation
For low
For high

Common reasons for high ALP:

  • Cholestatic liver injury – biliary obstruction, acute cholecystitis, cholangitis, cirrhosis, hepatic tumors.

    Bone/osteoblastic activity – Paget’s disease, osteomalacia/rickets, fracture healing, growth spurts, hyperparathyroidism, bone metastases.

    Gut/intestinal mucosa issues – IBS, celiac disease, intestinal ischemia; kidney disease; various malignancies; vitamin D deficiency; hyperthyroidism; rheumatoid arthritis; sickle cell crises.

    Medications – birth control pills, allopurinol, colchicine, antibiotics, fluorides, verapamil, nicotinic acid, vigorous exercise.

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