Glucose in Serum

Primary blood sugar measured after 12 hour overnight fasting. Reflects baseline glucose metabolism and is influenced by recent carbohydrate intake, acute stress, and physical activity.
Also known as:
Fasting Glucose
S-glucose
BS
.

Glucose ranges

Interpret your result
"Normal" lab range for Glucose is between 72 and 100 mg/dL:
72
100
According to OptimalDX, Glucose should be between 75 and 86 mg/dL:
75
86
Lowest all cause mortality was associated with Glucose between 80 and 94 mg/dL:
80
94
Optimal range
Optimal range for Glucose appears to be between 75 and 88 mg/dL:
65
75
88
100
250
Why this optimal range?
Preliminary range is based on functional health organizations including but not limited to those listed above.

What a low value may mean:

Common reasons for low Glucose:

  • True fasting hypoglycemia is most often seen with diabetes treatment — excess insulin, sulfonylureas, or meglitinides.

    A low glucose result can sometimes be false, especially if the blood sample was not processed quickly enough.

    Other causes include alcohol intake especially without adequate food, prolonged fasting or malnutrition, critical illness or sepsis, liver, kidney, or severe heart failure, adrenal or pituitary insufficiency, insulin-secreting tumors (insulinoma), and some non-diabetes medications.

    ,

What a high value may mean:

Common reasons for high Glucose:

  • High fasting glucose (hyperglycemia) most commonly reflects prediabetes, insulin resistance, or diabetes (type 1, type 2, gestational).

    Other causes: pancreatic damage (chronic pancreatitis, hemochromatosis), endocrine disorders that drive insulin resistance (Cushing syndrome, acromegaly, pheochromocytoma), acute physiologic stress or illness, and medications such as glucocorticoids, phenytoin, statins, and estrogens.

    ,

Images:

Fasting glucose increase during aging

Fasting glucose increase during aging

Fasting glucose was associated with all-cause mortality

Fasting glucose was associated with all-cause mortality

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Zsolt Szabo
Zsolt Szabo
Precision Health Consultant for Longevity Clinics

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I am particularly interested in research on biomarkers associated with all-cause mortality and on defining optimal reference ranges.