SHBG in Serum

Sex hormone binding globulin is produced by the liver and binds to sex hormones (testosterone, DHT, estradiol), regulating their bioavailability to tissues.

Also known as:

Sex hormone-binding globulin

S-SHBG

SHBG ranges for

Interpret your result

"Normal" lab range for SHBG is between 16.5 and 55.9 nmol/L for males:

16.5

55.9

According to Peter Attia, SHBG should be below 60 nmol/L for males:

According to OptimalDX, SHBG should be between 40 and 46 nmol/L for males:

Optimal range

Optimal range for SHBG appears to be between 25 and 46 nmol/L for males:

120

Why this optimal range?

Preliminary range is based on functional health organizations including but not limited to those listed above.

This page is marked as a work-in-progress.

The optimal range is derived from a limited number of sources and is subject to change.

Your interpretation

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About the site author
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Zsolt Szabo
Precision Health Consultant for Longevity Clinics, Biohacker, and Software Engineer

Please send me relevant research and feedback.

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I am particularly interested in research on biomarkers associated with all-cause mortality and on defining optimal reference ranges.